Quinine Sulfate Tablet 300mg

• Powder: No
• Customized: Customized
• Certification: GMP, Copp
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Model NO.: ANTI-08-08
• Transport Package: Level 3
• Specification: 300MG, 10*10/BOX
• Trademark: Serumpharm
• Origin: China
• HS Code: 2901231000

Product Description

QUININE SULFATE TABLET 300MG

Specification: 300MG, 10*10/BOX
Trademark: Serumpharm
Support OEM/ODM: Yes
Mini. Order: 10000 Boxes
Delivery Time: 30~60 Days
Trade Term: FOB,CIF
Payment Term: T/T,L/C
Standard Available: CP,BP
Documents: GMP,COPP,CTD

QUININE SULFATE TABLET 300MG

Indications:
For the treatment of chloroquine resistant falciparum malaria in adults and children aged 5 years or older (and ≥ 20kg)
Dosage and administration:
Posology
Treatment of chloroquine resistant falciparum malaria
Adults (including the elderly) and children aged 12 years and over: 600mg of quinine sulfate given every 8 hours for 7 days. The dose may depend upon the size of the patient, severity of infection, and evidence of renal or liver disease (when the intervals should be increased), due to a prolonged half-life of the drug.
Paediatric population
Treatment of chloroquine resistant falciparum malaria
The dosage regimen for children by mouth is 10mg of quinine sulfate per kg body weight given every 8 hours for 7 days. Quinine sulfate 200mg tablets are not suitable for children weighing less than 20kg or less than 5 years old.
Method of administration
For oral administration.
Contraindications:
- Hypersensitivity to the active substance or to any of the excipients
- Tinnitus
- Optic neuritis
- Haemoglobinuria
- Myasthenia gravis (quinine may cause severe respiratory distress and dysphagia in these patients)
Precautions:
Chinchonism
Administration of quinine may give rise to cinchonism, which is generally more severe in overdose, but may also occur in normal therapeutic doses.  
Hypersensitivity
Hypersensitivity to quinine may also occur with symptoms of cinchonism together with urticaria, flushing, pruritus, rash, fever, angioedema, dyspnoea and asthma.
Cardiac disorders
Quinine should be used with caution in patients with atrial fibrillation, conduction defects and heart block or other serious heart disease.
Glucose-6-Phosphate Dehydrogenase (G-6-PD) Deficiency
The administration of quinine to a patient who has previously been suffering from a chronic and inadequately controlled malarial infection may precipitate an attack of Blackwater fever.  
Quinine should not be withheld from pregnant women who have life threatening malaria.
Treatment should be monitored in all patients in case signs of resistance develop.
Thrombocytopenia
Quinine may cause unpredictable serious and life-threatening thrombocytopenia, which is thought to be an idiosyncratic hypersensitivity reaction.
Drug interactions:
Caution is advised when administering quinine with drugs which could prolong the QT interval.
Antiarrhythmics
Antibacterials
Anticoagulants
Antihistamines
Antimalarials
Antipsychotics
Hypoglycaemics
Suxamethonium
Ulcer-healing drugs
Anti-epileptics
Storage:
Do not store above 25°C.



 

Jiangxi Serum Pharma Industries Co.,Ltd. is a professional medical and pharmaceutical products supplier in China. We have been focused on exporting Biological products,Vaccines,Western medicines, APIs, Intermediates and medical products over 10 years, accumulating a wealth of experience. Our products have been exported to more than 30 countries, mainly in Asia, Africa, South America, Middle East and Europe, such as Philippines, Bangladesh,Laos,Cambodia, Kyrghyzstan, Cameroon, Guinea, Nigeria, Liberia, Mali, Yemen, Turkey, Chile, Australia and so on.Our finished products have won great popularity with reliable quality and competitive price,we have numerous end-users and good market reputation. 

We have developed advanced into the leading enterprise in pharmaceutical overseas exporting industry after years of efforts.Our products, including API and finished formulation, have been accredited with various certificates, such as Chinese GMP certificate, ISO9001 quality certificate.

The company has established close cooperation relations with domestic manufacturers of biological products, vaccines, raw material medicines and auxiliary materials, and has shared resources and complementary advantages. we are committed to the development and penetration of the international market and provide customers with quality assurance. We provide various pharmaceutical APIs and finished products with top quality at reasonable price and better after-sales service.

Our company has established a perfect quality assurance system in strict accordance with China's GMP requirements. The entire process from raw material procurement to finished product shipment is controlled by the quality assurance department.All raw materials are provided by selected reliable suppliers and carefully inspected by the Quality Assurance Department before use.

Excellence, Professionalism, and integrity are our cultures. We will offer good quality products with competitive prices and fast delivery for our customers. We are looking forward to setting up long-term cooperation relationship with you.